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KMID : 1134120150180030291
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Journal of Breast Cancer
2015 Volume.18 No. 3 p.291 ~ p.295
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Breast Cancer Arising Adjacent to an Involuting Fibroadenoma: Serial Changes in Radiologic Features
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Park Chae-Jung
Kim Eun-Kyung
Woo Ha-young
Moon Hee-Jung
Yoon Jung-Hyun
Kim Min-Jung
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Abstract
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Fibroadenoma is a common benign breast lesion and its malignant transformation is rare. There have been several case reports and studies that retrospectively reviewed breast cancers that arose within fibroadenomas; however, none of these studies reported serial changes in radiologic features of the cancer, including findings from mammography and ultrasound (US). We report a case of breast cancer arising adjacent to an involuting fibro adenoma in a 39-year-old woman who was undergoing serial follow-up after her fibroadenoma was diagnosed. Seven years after her diagnosis, the lesion showed evidence of coarse calcifications, a typical sign of involution. Four years later, US revealed a newly developed hypoechoic lesion with irregular margins and peripherally located calcifications adjacent to the fibroadenoma. A core biopsy was performed, and histopathological examination resulted in a diagnosis of invasive ductal carcinoma. When new suspicious features are observed in a fibroadenoma, radiologists should raise the concern for breast cancer and proceed with diagnosis and treatment accordingly.
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KEYWORD
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Breast neoplasms, Fibroadenoma, Magnetic resonance imaging, Mammography, Ultrasonography
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